Kontakt
Wie einkaufen
Versand
Kaufberater
Pharmacogenetic Study of Drug Metabolizing Enzyme CYP3A4
Englisch
102 b
Bis zu 30 Tage Rückgaberecht
Kunden kauften auch
Pharmacogenetics is generally regarded as the study of genetic variation that gives rise to different responses to drugs. It may be possible to predict therapeutic failures or severe adverse drug reactions in individual patients by testing for important DNA sequence variations or polymorphisms in key drug-metabolizing enzymes, receptors, transporters, etc. In this book, we characterized methods for genotyping CYP3A4 2, CYP3A4 4, CYP3A4 5, CYP3A4 6, and CYP3A4 10 alleles among Bangladeshi population in 70 healthy adult unrelated volunteers. Cytochrome P450 3A (CYP3A) subfamily is responsible for the metabolism of more than 60% drugs used by the human including clinically important drugs like nifedipine, cyclosporine, erythromycin, midazolam, triazolam, digitoxin, lidocaine, and quinine etc. Venous blood samples were collected from 70 healthy Bangladeshi volunteers. Genomic DNA was extracted from these blood samples and PCR-RFLP analysis was employed to genotype important alleles of CYP3A4. CYP3A4 2, CYP3A4 4, CYP3A4 5, CYP3A4 6, and CYP3A4 10 alleles were found to be absent in Bangladeshi population, which are common in other ethnic groups
Informationen zum Buch
Englisch
Verschenken Sie dieses Buch noch heute
Es ist ganz einfach
1 Legen Sie das Buch in Ihren Warenkorb und wählen Sie den Versand als Geschenk 2 Wir schicken Ihnen umgehend einen Gutschein 3 Das Buch wird an die Adresse des beschenkten Empfängers geliefertDas könnte Sie auch interessieren
/
Broschur
9.29
€
/
Broschur
9.99
€
/
Broschur
13.69
€
/
Broschur
42.69
€
