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Digital Smile Design is a method that allows us to digitally design the smile of our patients, by obtaining a simulation and pre-visualization of the therapeutic result. It allows the patient to have awareness from the beginning of the treatment plan and for them to be the first interpreter in the aesthetic and functional rehabilitation of their oral cavity, and on the other hand, it allows the specialist to tune in better to the expectations and needs of the patient, in order to pursue their shared goals. These protocols therefore enables us to substantiate the clinical case and analyse the outcome, for presenting to the patient, in a clear way, the usefulness of being able to program the rehabilitation and interface clearly with the help of other professional figures. This book contains all the essentials, concepts and techniques of Digital Smile Design along with its appropriate clinical application and usefulness in the present era of digitalization.